I have opposed
ideas calling Neolithic Europeans Near Easterners, because all my analyses show
significant later Near Eastern admixture in Mediterranean region, clearly
differing from ancient Neolithic farmer genes.
This implied at least equal genetic change in Near East than in Europe from
the Neolithic Era to the present. How can
we call European Neolithic farmers Near Easterners if European Neolithic samples are closer modern European
than modern Near Easterners? Really, my analyses prove this. Closest European for ancient
Neolithic farmers are Albanians and Sardinians.
Albanian yDna E is one of the highest in Europe, after
Kosovo, which can predict same thing. Unfortunately Kosovo samples are
not available. It is very possible that European Neolithic
farmers came from Near East through Anatolia, but we have not yet genetic evidences
proving it and the process was probably much more complex than a simple
migration to Europe from what we now understand as Near East.
My analysis
consists of following steps:
1 pre-selection
of data (Haak et al. 2015)
2 running
PCA to find out European Neolithic genetic cluster based on ancient samples of
highest quality
3 running new
PCA and Fst-figures to see genetic distance
This is a
very simple procedure and I know well that Fst-distances obtained using ancient
genomes are not comparable to distances between modern populations due to lower
scanning quality, but I don’t even try
do it, I only compare ancient data to modern one, so possible quality problems
doesn’t exist in same extent.
Please notice also many Jewish groups I included now into my data.
PCA, click here to expand.
Fst-distances of Bedouins (BedouinB, used as a Near Eastern proxy by Haak), click here.
This detail interested me:
ReplyDeleteBedouinB Finnish 0.047 0.0009
Early_Neolithic Finnish 0.059 0.0010
Early neolithic europeans are more distant from finns by Fst than bedouins!!!
Now of course this is curious, because finns are least likely of europeans to have post-neolithic middle eastern ancestry, and bedouins are least likely of near easterners to have both african or Ancestral northern eurasian ancestry.
So question from your analysis is: Why are european neolithic farmers so allergic to everyone?
No, I wrote that we can't compare Fst-distances to ancient and present-day genomes. I wrote about this because I knew that I have to answer to this question :)
Delete"This is a very simple procedure and I know well that Fst-distances obtained using ancient genomes are not comparable to distances between modern populations due to lower scanning quality, but I don’t even try do it, I only compare ancient data to modern one, so possible quality problems doesn’t exist in same extent."
Anyways, the results are otherwise predictable: the early neolithics are similar to europeans with particularly low ANE and WHG. I am still holding out by my theory that they were extremely inbred middle eastern hicks who got lost in europe :P
DeleteMy aim is to give right answers, not to be allergic. It was you who made this conclusion, I only made statistics.
DeleteHmm???
DeleteI said the sample (early neolithic europeans) were allergic to others, judging by PCA position and Fst numbers. I said nothing insulting towards you, Sir, I'm sorry for lack of clarity.
Okay, I thought that you commented something regarding my blog entry. I really have always understood that we shouldn't name early Europeans as Near Easterners, because present-day Near Easterners are not same as they were. I have had some debate about this question and some people insist that EEF = Near Easterners.
DeleteActually early European Neolithic samples are very close to South Europeans, being closer modern Europeans than many other ancient samples. Modern Europeans are more mixed.
Spageti, the fst-distances are elevated because the neolithic farmers are an ancient population and bedouins a modern one. The Bedouins are also closer to Sardinians than the neolithic farmers are if you just look at those fst-distances, even though the farmers still cluster with or next to Sardinians on PCA's while Bedouins do not.
DeleteThe fst-distances are good for a relative comparison, showing Sardinians and Albanians are closest to the neolithic farmers among living populations, but not so much for an absolute one - which would suggest the farmers are less related to Europeans than purely Near Eastern Bedouins.
Neolithic Europeans weren't Near Eastern in the modern sense. They introduced a new form of ancestry in Europe, called Basal Eurasian, which came from the Near East and maybe also the Balkans.
ReplyDeleteNo one is saying they're exactly the same as Near easterns today. We're saying they derived largely from the same ancient Near Eastern people as do modern Near Easterns. Where did farming come from? The Near East. So, it's quite obvious that's where the shared ancestry comes from.
You also have to be careful with simplistic conclusions based on EV13 in Europe. At least in Kosovars, their high rate of V13 is due to recent founder effect - as a subset of Albanians moved into the Kosovo plain and multiplied a hundred-fold under Ottoman auspices.
ReplyDelete